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An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive Disorder

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Trial Profile

An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive Disorder

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Mar 2022

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At a glance

  • Drugs AV 101 (Primary)
  • Indications Major depressive disorder
  • Focus Proof of concept; Therapeutic Use

    • Most Recent Events

    • 31 Mar 2020 Results assessing whether 4-Cl-KYN has rapid antidepressant effects in individuals with treatment-resistant depression (TRD) published in the International Journal of Neuropsychopharmacology
    • 04 Dec 2019 Status changed from recruiting to completed.
    • 29 Jun 2017 According to a VistaGen Therapeutics media release, the company expects top-line results from the study during the first half of 2018.

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