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Study to Evaluate the Effect of Roflumilast 500 μg on Exacerbation Rate in Subjects With Chronic Obstructive Pulmonary Disease (COPD) Treated With a Fixed-Dose Combination of Long-Acting Beta Agonist and Inhaled Corticosteroid (LABA/ICS)

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Study to Evaluate the Effect of Roflumilast 500 μg on Exacerbation Rate in Subjects With Chronic Obstructive Pulmonary Disease (COPD) Treated With a Fixed-Dose Combination of Long-Acting Beta Agonist and Inhaled Corticosteroid (LABA/ICS)

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 23 May 2018

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At a glance

  • Drugs Roflumilast (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Therapeutic Use
  • Acronyms RE2SPOND
  • Sponsors AstraZeneca; Forest Laboratories

    • Most Recent Events

    • 15 May 2018 Pooled analysis results from REACT and RE2SPOND studies (n=4287) were published in the American Journal of Respiratory and Critical Care Medicine
    • 24 May 2017 Results of pooled analysis from REACT and RE2SPOND studies evaluating the efficacy of roflumilast in the overall population and in patients with a history of COPD-related hospitalization presented at the 113th International Conference of the American Thoracic Society.
    • 24 May 2017 Results assessing effects of roflumilast on cough and sputum production, EXACT-PRO symptom subdomains, presented at the 113th International Conference of the American Thoracic Society

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