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A Multicentre, Double-blind, Randomised Parallel Group, Placebo- controlled Study of the Effect of long-term treatment with Sativex on Cognitive Function and Mood of Patients with Spasticity due to Multiple Sclerosis

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Trial Profile

A Multicentre, Double-blind, Randomised Parallel Group, Placebo- controlled Study of the Effect of long-term treatment with Sativex on Cognitive Function and Mood of Patients with Spasticity due to Multiple Sclerosis

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 16 Jan 2023

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At a glance

  • Drugs Nabiximols (Primary)
  • Indications Multiple sclerosis; Muscle spasticity
  • Focus Therapeutic Use
  • Sponsors GW Pharmaceuticals; Jazz Pharmaceuticals Inc

    • Most Recent Events

    • 28 Oct 2022 Results of post hoc analysis assessing the long-term dosage of nabiximols, to evaluate real-world dosing and to investigate the association between dosage and premature study discontinuation in MS-related spasticity from GWMS1137 (n=62) and GWSR10128 (N=765) studies, presented at the 38th Congress of the European Committee for Treatment and Research in Multiple Sclerosis.
    • 22 Apr 2021 Results assessing effect of nabiximols on depression, suicidality, and cognition using data from GWSP0604 (12 weeks; n=241) and GWMS1137 (48 weeks; n=121) trials in persons with multiple sclerosis with inadequately managed spasticity, presented at the 73rd Annual Meeting of the American Academy of Neurology.
    • 13 Apr 2021 According to a GW Pharmaceuticals media release, results from two studies GWSP0604 and GWMS1137 (abstract no P15.185) presented at the 2021 American Academy of Neurology

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