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A multicenter, randomized, blinded, double-dummy, placebo controlled, 3-period cross-over study to evaluate the effect of QVA149 on patient reported dyspnea in moderate to severe chronic obstructive pulmonary disease (COPD), using tiotropium as an active control.

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Trial Profile

A multicenter, randomized, blinded, double-dummy, placebo controlled, 3-period cross-over study to evaluate the effect of QVA149 on patient reported dyspnea in moderate to severe chronic obstructive pulmonary disease (COPD), using tiotropium as an active control.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Feb 2015

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At a glance

  • Drugs Glycopyrrolate/indacaterol (Primary) ; Tiotropium bromide
  • Indications Chronic obstructive pulmonary disease
  • Focus Therapeutic Use
  • Acronyms BLAZE
  • Sponsors Novartis

Most Recent Events

  • 23 Sep 2013 Results from this trial contributed to the approval of glycopyrrolate/indacaterol, delivered via the Ultibro Breezhaler, by the European Commission according to a Vectura Group media release.
  • 11 Sep 2013 Results presented at the 23rd Annual Congress of the European Respiratory Society.
  • 11 Sep 2013 Results presented at the 23rd Annual Congress of the European Respiratory Society.

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