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A Multicentre Randomized Controlled Trial of the Use of Extended Peri-Operative Low Molecular Weight Heparin to Improve Cancer Specific Survival Following Surgical Resection of Colon Cancer

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Trial Profile

A Multicentre Randomized Controlled Trial of the Use of Extended Peri-Operative Low Molecular Weight Heparin to Improve Cancer Specific Survival Following Surgical Resection of Colon Cancer

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 25 Jan 2024

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At a glance

  • Drugs Tinzaparin sodium (Primary)
  • Indications Adenocarcinoma; Cancer metastases; Colon cancer; Colorectal cancer; Deep vein thrombosis; Pulmonary embolism; Rectal cancer; Venous thromboembolism
  • Focus Pharmacodynamics; Therapeutic Use
  • Acronyms PERIOP-01
  • Most Recent Events

    • 12 Dec 2023 Results of post hoc analysis (n=614) assessing Efficacy and Safety of Extended Duration Postoperative Thromboprophylaxis with Low-Molecular-Weight-Heparin Among Subgroups of Patients Undergoing Surgical Resection of Colorectal Cancer presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 20 Sep 2022 Primary endpoint has not been met (Disease Free Survival), as per Results published in the BMJ
    • 20 Sep 2022 Results published in the BMJ

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