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Randomized, Double-Blind, Placebo-Controlled Phase I/II Study of the Safety and Efficacy of Intracoronary Delivery of Allogeneic Cardiosphere-Derived Cells in Patients With a Myocardial Infarction and Ischemic Left Ventricular Dysfunction

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Trial Profile

Randomized, Double-Blind, Placebo-Controlled Phase I/II Study of the Safety and Efficacy of Intracoronary Delivery of Allogeneic Cardiosphere-Derived Cells in Patients With a Myocardial Infarction and Ischemic Left Ventricular Dysfunction

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 12 Apr 2024

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At a glance

  • Drugs CAP-1002 (Primary)
  • Indications Left ventricular dysfunction; Myocardial infarction
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ALLSTAR
  • Sponsors Capricor
  • Most Recent Events

    • 04 Aug 2020 Primary endpoint (relative percentage improvement in infarct size assessed by MRI for the CAP-1002 group compared to the placebo group at Months 6 and 12 post-infusion) has not been met, according to Results published in the European Heart Journal.
    • 04 Aug 2020 Results published in the European Heart Journal
    • 04 Apr 2019 Status changed from active, no longer recruiting to discontinued.
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