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REALISTIC: A Phase I, Dose Escalation Trial Of Recombinant Listeria Monocytogenes (Lm)-Based Vaccine Encoding Human Papilloma Virus Genotype 16 Target Antigens (ADXS11-001) In Patients With HPV-16 +ve Oropharyngeal Carcinoma

Trial Profile

REALISTIC: A Phase I, Dose Escalation Trial Of Recombinant Listeria Monocytogenes (Lm)-Based Vaccine Encoding Human Papilloma Virus Genotype 16 Target Antigens (ADXS11-001) In Patients With HPV-16 +ve Oropharyngeal Carcinoma

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 05 Sep 2022

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At a glance

  • Drugs Axalimogene filolisbac (Primary)
  • Indications Oropharyngeal cancer; Squamous cell cancer
  • Focus Adverse reactions
  • Acronyms REALISTIC

Most Recent Events

  • 04 Apr 2016 Status changed to discontinued as per ISRCTN: Current Controlled Trials.
  • 04 Dec 2013 Accrual to date is 5% according to United Kingdom Clinical Research Network record.
  • 13 Nov 2013 Accrual to date is 2% according to United Kingdom Clinical Research Network record.

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