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Prospective, explorative trial for the detection of circulating cell-free tumor DNA in the plasma of patients with gastrointestinal stromal tumors (GIST) harboring activating mutations of CKIT or PDGFRA pre/post surgery or pre/under treatment with a tyrosine kinase inhibitor or progressive disease irrespective of current or planned treatment. An open-label, non-randomized, multicenter phase IIIb clinical trial.

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Trial Profile

Prospective, explorative trial for the detection of circulating cell-free tumor DNA in the plasma of patients with gastrointestinal stromal tumors (GIST) harboring activating mutations of CKIT or PDGFRA pre/post surgery or pre/under treatment with a tyrosine kinase inhibitor or progressive disease irrespective of current or planned treatment. An open-label, non-randomized, multicenter phase IIIb clinical trial.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 21 Dec 2015

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At a glance

  • Drugs Imatinib (Primary) ; Sunitinib (Primary)
  • Indications Gastrointestinal stromal tumours
  • Focus Pharmacogenomic; Therapeutic Use
  • Acronyms CF DNA GIST
  • Most Recent Events

    • 19 Dec 2015 Status changed from recruiting to completed, according to European Clinical Trials Database record.
    • 01 Nov 2011 New trial record
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