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A Cancer Research UK Phase I dose escalation trial of oral VEGFR and EGFR inhibitor, Vandetanib in combination with the oral MEK inhibitor, Selumetinib (VanSel-1) in solid tumours (dose escalation) and NSCLC (expansion cohort)

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Trial Profile

A Cancer Research UK Phase I dose escalation trial of oral VEGFR and EGFR inhibitor, Vandetanib in combination with the oral MEK inhibitor, Selumetinib (VanSel-1) in solid tumours (dose escalation) and NSCLC (expansion cohort)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Oct 2022

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At a glance

  • Drugs Selumetinib (Primary) ; Vandetanib (Primary)
  • Indications Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions
  • Acronyms VanSel1

    • Most Recent Events

    • 06 May 2021 Status changed from active, no longer recruiting to completed.
    • 26 Jan 2021 Planned End Date changed from 1 Oct 2020 to 1 Mar 2021.
    • 26 Jan 2021 Planned primary completion date changed from 1 Oct 2020 to 1 Mar 2021.

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