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A Phase I Open Label Safety Study to Evaluate the Pharmacokinetic Profile and Tolerance of Mibefradil Dose Finding in Subjects With Recurrent High-Grade Glioma Undergoing Standard, Repeated Temozolomide Treatment

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A Phase I Open Label Safety Study to Evaluate the Pharmacokinetic Profile and Tolerance of Mibefradil Dose Finding in Subjects With Recurrent High-Grade Glioma Undergoing Standard, Repeated Temozolomide Treatment

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Jun 2024

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At a glance

  • Drugs Mibefradil (Primary) ; Temozolomide
  • Indications Anaplastic astrocytoma; Astrocytoma; Ependymoma; Glioblastoma; Glioma; Oligodendroglioma
  • Focus Adverse reactions

    • Most Recent Events

    • 23 Dec 2015 Status changed from active, no longer recruiting to completed, as reported by ClinicalTrials.gov.
    • 28 Jul 2015 Planned primary completion date changed from 1 Jun 2015 to 1 Sep 2015 as reported by ClinicalTrials.gov
    • 29 May 2015 Results presented at the 51st Annual Meeting of the American Society of Clinical Oncology.

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