A Multi-arm Dose-finding Phase Ib Multicenter Study of Imatinib in Combination With the Oral Phosphatidyl-inositol 3-kinase (PI3-K) Inhibitor BKM120 in Patients With Gastrointestinal Stromal Tumor (GIST) Who Failed Prior Therapy With Imatinib and Sunitinib.
Phase of Trial: Phase I
Latest Information Update: 11 Jul 2017
At a glance
- Drugs Buparlisib (Primary) ; Imatinib (Primary)
- Indications Gastrointestinal stromal tumours
- Focus Adverse reactions
- Sponsors Novartis
- 16 Nov 2016 Status changed from active, no longer recruiting to completed.
- 21 Apr 2016 Planned End Date changed from 1 Jul 2016 to 1 Dec 2016.
- 21 Apr 2016 Planned primary completion date changed from 1 Jul 2016 to 1 Dec 2016.