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An Open-label, Single-sequence, Four-treatment Period Study to Evaluate Pharmacokinetic and Pharmacodynamic Interactions Between E5501 and Verapamil, and E5501 and Cyclosporine, Known P-glycoprotein Inhibitors in Healthy Subjects.

Trial Profile

An Open-label, Single-sequence, Four-treatment Period Study to Evaluate Pharmacokinetic and Pharmacodynamic Interactions Between E5501 and Verapamil, and E5501 and Cyclosporine, Known P-glycoprotein Inhibitors in Healthy Subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 May 2012

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At a glance

  • Drugs Avatrombopag (Primary) ; Ciclosporin; Verapamil
  • Indications Atrial fibrillation; Ischaemic heart disorders; Paroxysmal supraventricular tachycardia; Psoriasis; Rheumatoid arthritis; Supraventricular tachycardia
  • Focus Pharmacokinetics
  • Most Recent Events

    • 18 May 2012 Actual patient number 36 added according to ClinicalTrials.gov.
    • 18 May 2012 Actual end date (Mar 2012) added as reported by ClinicalTrials.gov.
    • 18 May 2012 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
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