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A Phase I/II Trial to Assess Safety and Tolerability of an Oral Aurora Kinase A Inhibitor, MLN8237, In Combination With Erlotinib In Patients With Recurrent or Metastatic Non-Small Cell Lung Cancer

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Trial Profile

A Phase I/II Trial to Assess Safety and Tolerability of an Oral Aurora Kinase A Inhibitor, MLN8237, In Combination With Erlotinib In Patients With Recurrent or Metastatic Non-Small Cell Lung Cancer

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 23 May 2018

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At a glance

  • Drugs Alisertib (Primary) ; Erlotinib
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 14 May 2018 Status changed to discontinued as Phase I portion completed. Phase II will open pending amendment approval.
  • 08 Sep 2017 Planned End Date changed from 31 Jul 2018 to 31 Jul 2019.
  • 08 Sep 2017 Planned primary completion date changed from 27 Aug 2017 to 27 Aug 2018.

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