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A Phase 2b, Double-blind, Randomized, Placebo-controlled, Dose-finding Study to Evaluate Efficacy of a Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD) With Persistent Regurgitation With or Without Heartburn.

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Trial Profile

A Phase 2b, Double-blind, Randomized, Placebo-controlled, Dose-finding Study to Evaluate Efficacy of a Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD) With Persistent Regurgitation With or Without Heartburn.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Jun 2021

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At a glance

  • Drugs SPD 557 (Primary) ; Proton pump inhibitors
  • Indications Gastro-oesophageal reflux
  • Focus Pharmacogenomic; Therapeutic Use
  • Sponsors Shire
  • Most Recent Events

    • 01 May 2013 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 25 Apr 2013 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.
    • 23 Jun 2012 Additional location (Hungary) added as reported by European Clinical Trials Database record.

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