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Effect of Roflumilast 500 μg Tablets Once Daily at Acute COPD Exacerbations Treated With Standard Therapy of Oral Steroids and Antibiotics. A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial.

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Trial Profile

Effect of Roflumilast 500 μg Tablets Once Daily at Acute COPD Exacerbations Treated With Standard Therapy of Oral Steroids and Antibiotics. A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial.

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Roflumilast (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Therapeutic Use
  • Acronyms TREAT
  • Sponsors Takeda

Most Recent Events

  • 01 Feb 2017 Results published in the American Journal of Respiratory and Critical Care Medicine
  • 18 May 2016 Primary endpoint has not been met. (Change in sputum neutrophil counts [cells/g sputum] from Day 1 to Day 14 post exacerbation), as per results presented at the 112th International Conference of the American Thoracic Society.
  • 18 May 2016 Results presented at the 112th International Conference of the American Thoracic Society.

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