Trial Profile

A phase I trial of MK-2206 and hydroxychloroquine in solid tumors, melanoma, renal and prostate cancer to examine the role of autophagy in tumorigenesis

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 24 Apr 2026

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At a glance

Drugs MK 2206 (Primary) ; Hydroxychloroquine
Indications Colon cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Prostate cancer; Renal cell carcinoma; Solid tumours
Focus Adverse reactions

Most Recent Events

03 Apr 2026 Planned End Date changed from 19 Mar 2026 to 31 Mar 2027.
21 Mar 2025 Planned End Date changed from 7 Mar 2025 to 19 Mar 2026.
30 Dec 2019 Planned primary completion date changed from 1 Dec 2019 to 1 Mar 2020.

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