Trial Profile

A Phase I, Dose-escalation Trial of Rituxan and Bendamustine in Combination With Bruton's Tyrosine Kinase Inhibitor, PCI-32765, in Patients With Relapsed Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Indolent Non-Hodgkin's Lymphoma.

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 31 Jul 2026

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At a glance

Drugs Bendamustine (Primary) ; Ibrutinib (Primary) ; Rituximab (Primary)
Indications Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
Focus Adverse reactions

22 Jul 2026 Planned End Date changed from 1 Sep 2026 to 1 Dec 2026.
22 Jul 2026 Planned primary completion date changed from 1 Jul 2026 to 1 Dec 2026.
23 Mar 2026 Planned End Date changed from 1 Mar 2026 to 1 Sep 2026.

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