Trial Profile

A Phase I, Dose-escalation Trial of Rituxan and Bendamustine in Combination With Bruton's Tyrosine Kinase Inhibitor, PCI-32765, in Patients With Relapsed Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Indolent Non-Hodgkin's Lymphoma.

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 02 Jun 2025

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At a glance

Drugs Bendamustine (Primary) ; Ibrutinib (Primary) ; Rituximab (Primary)
Indications Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
Focus Adverse reactions

28 May 2025 Planned End Date changed from 1 May 2025 to 1 Oct 2025.
28 May 2025 Planned primary completion date changed from 1 May 2025 to 1 Oct 2025.
26 Feb 2025 Planned End Date changed from 31 Dec 2024 to 1 May 2025.

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