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Combination Immunotherapy With Herceptin and the HER2 Vaccine E75 in Low and Intermediate HER2-expressing Breast Cancer Patients to Prevent Recurrence

Trial Profile

Combination Immunotherapy With Herceptin and the HER2 Vaccine E75 in Low and Intermediate HER2-expressing Breast Cancer Patients to Prevent Recurrence

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Nelipepimut-S (Primary) ; Trastuzumab (Primary) ; Sargramostim
  • Indications Early breast cancer; HER2 negative breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use
  • Most Recent Events

    • 18 Feb 2020 Primary endpoint (Disease-free survival (DFS)) has not been met, as per Results published in the Clinical Cancer Research
    • 18 Feb 2020 Results published in the Clinical Cancer Research
    • 04 Jun 2019 Results assessing ex vivo and in vivo immune responses (IR) presented at the 55th Annual Meeting of the American Society of Clinical Oncology
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