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A Double-Blind, Randomized, Placebo-Controlled, Age Descending and Expansion Phase 2 Study to Investigate the Safety and Immunogenicity of a Tetravalent Chimeric Dengue Vaccine in Healthy Volunteers Between the Ages of 1.5 - 45 Years

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A Double-Blind, Randomized, Placebo-Controlled, Age Descending and Expansion Phase 2 Study to Investigate the Safety and Immunogenicity of a Tetravalent Chimeric Dengue Vaccine in Healthy Volunteers Between the Ages of 1.5 - 45 Years

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Apr 2023

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At a glance

  • Drugs Dengue tetravalent vaccine Takeda (Primary) ; Dengue tetravalent vaccine Takeda (Primary)
  • Indications Dengue
  • Focus Adverse reactions; Pharmacodynamics
  • Sponsors Takeda

    • Most Recent Events

    • 03 Dec 2022 Results investigating the ability of Antibodies Produced in Response to a Live-Attenuated Dengue Vaccine are Functional in Activating the Complement System published in the Journal of Infectious Diseases
    • 03 Feb 2021 Results assessing polyclonal antibody avidity to all four DENV serotypes using sera from two phase 2 trials (DEN-203 and DEN-204) published in the Journal of Infectious Diseases
    • 13 Jul 2020 Long term safety and immunogenicity results published in the Journal of Infectious Diseases.

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