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A Prospective, Multinational, Open-Label, Single-Arm, Explorative Study To Evaluate The Tolerability And Efficacy Of Lacosamide When Added To Levetiracetam With Withdrawal Of The Concomitant Sodium Channel Blocking Antiepileptic Drug In Subjects With Uncontrolled Partial-Onset Seizures.

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Trial Profile

A Prospective, Multinational, Open-Label, Single-Arm, Explorative Study To Evaluate The Tolerability And Efficacy Of Lacosamide When Added To Levetiracetam With Withdrawal Of The Concomitant Sodium Channel Blocking Antiepileptic Drug In Subjects With Uncontrolled Partial-Onset Seizures.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 Oct 2021

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At a glance

  • Drugs Lacosamide (Primary) ; Levetiracetam
  • Indications Partial epilepsies
  • Focus Registrational; Therapeutic Use
  • Acronyms OCToPOS; VERVE
  • Sponsors UCB
  • Most Recent Events

    • 24 May 2017 Planned locations also included Austria, Canada, Hungary, Netherlands, Switzerland.
    • 01 Apr 2017 Results assessing efficacy and of post hoc analysis (n=51) assessing effectiveness of LCM among patients treated within dose range (less than or equal to 400 Mg/ Day), published in the Acta Neurologica Scandinavica
    • 25 Apr 2015 Results presented at the 67th Annual Meeting of the American Academy of Neurology.
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