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A Randomized, Open-label, Phase 2 Trial of Sipuleucel-T With Concurrent Versus Sequential Administration of Abiraterone Acetate Plus Prednisone in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)

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A Randomized, Open-label, Phase 2 Trial of Sipuleucel-T With Concurrent Versus Sequential Administration of Abiraterone Acetate Plus Prednisone in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Sipuleucel-T (Primary) ; Abiraterone acetate; Prednisone
  • Indications Prostate cancer
  • Focus Pharmacodynamics
  • Acronyms STAMP
  • Sponsors Dendreon Corporation

    • Most Recent Events

    • 25 Feb 2021 Results for analyses of T cells from sipuleucel-T-treated subjects in STAMP showing direct lysis of cells that express prostate cancer target antigens through video recordings, published in the Journal of the National Cancer Institute
    • 15 Feb 2020 Results assessing association of humoral antigen spread with cytotoxic T lymphocyte activity after sipuleucel-T treatment in two studies (STAMP and STRIDE), presented at the 2020 Genitourinary Cancers Symposium.
    • 13 Feb 2020 Results published in the Dendreon corporation media release

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