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A Randomized, Two-Arm, Open-Label, Multicenter Phase II Trial Assessing the Efficacy and Safety of Pertuzumab Given in Combination With Trastuzumab Plus an Aromatase Inhibitor in First Line Patients With HER2-Positive and Hormone Receptor-Positive Advanced (Metastatic or Locally Advanced) Breast Cancer

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A Randomized, Two-Arm, Open-Label, Multicenter Phase II Trial Assessing the Efficacy and Safety of Pertuzumab Given in Combination With Trastuzumab Plus an Aromatase Inhibitor in First Line Patients With HER2-Positive and Hormone Receptor-Positive Advanced (Metastatic or Locally Advanced) Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 16 Feb 2023

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At a glance

  • Drugs Pertuzumab (Primary) ; Anastrozole; Docetaxel; Letrozole; Paclitaxel; Trastuzumab
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Therapeutic Use
  • Acronyms PERTAIN
  • Sponsors Roche

    • Most Recent Events

    • 30 Jan 2023 Results of final analysis were published in the Clinical Cancer Research
    • 07 Dec 2019 Status changed from active, no longer recruiting to completed.
    • 23 Oct 2019 Planned End Date changed from 26 Oct 2019 to 1 Nov 2019.

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