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Evaluation of Fosaprepitant's Effect on Drug Metabolism in Sarcoma Patients Receiving Ifosfamide-based Multi-day Chemotherapy Regimen

Trial Profile

Evaluation of Fosaprepitant's Effect on Drug Metabolism in Sarcoma Patients Receiving Ifosfamide-based Multi-day Chemotherapy Regimen

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 11 May 2022

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At a glance

  • Drugs Fosaprepitant (Primary) ; Ifosfamide (Primary) ; Antineoplastics; Dexamethasone; Doxorubicin; Mesna; Vincristine
  • Indications Chemotherapy-induced nausea and vomiting; Sarcoma
  • Focus Pharmacokinetics; Therapeutic Use

Most Recent Events

  • 11 Mar 2016 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
  • 02 Jun 2015 Primary endpoint has been met (Area under the drug concentration-time curve Ifosfamide AUC), according to an abstract presented at the 51st Annual Meeting of the American Society of Clinical Oncology.
  • 02 Jun 2015 Primary endpoint has been met (Complete Response), according to an abstract presented at the 51st Annual Meeting of the American Society of Clinical Oncology.

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