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An open-label, single-dose, two-treatment, randomized, cross-over study to investigate the effects of the SLCO2B1 c.1457C>T polymorphism and apple juice on the pharmacokinetics and pharmacodynamics of acebutolol in healthy Korean and Japanese volunteers.

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An open-label, single-dose, two-treatment, randomized, cross-over study to investigate the effects of the SLCO2B1 c.1457C>T polymorphism and apple juice on the pharmacokinetics and pharmacodynamics of acebutolol in healthy Korean and Japanese volunteers.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Acebutolol (Primary)
  • Indications Arrhythmias; Hypertension
  • Focus Pharmacodynamics; Pharmacogenomic; Pharmacokinetics

    • Most Recent Events

    • 20 Jun 2012 Biomarkers information updated
    • 19 Jun 2012 Actual end date (May 2012) added as reported by ClinicalTrials.gov.
    • 19 Jun 2012 Actual initiation date (Jan 2012) and actual patient no (16) added as reported by ClinicalTrials.gov.

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