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A Phase I/II Study of ABT-888, An Oral Poly(ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children With Newly Diagnosed Diffuse Pontine Gliomas (DIPG)

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A Phase I/II Study of ABT-888, An Oral Poly(ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children With Newly Diagnosed Diffuse Pontine Gliomas (DIPG)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Veliparib (Primary) ; Temozolomide
  • Indications Anaplastic astrocytoma; Astrocytoma; CNS cancer; Diffuse intrinsic pontine glioma; Glioblastoma; Glioma; Gliosarcoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 30 Mar 2018 Status changed from active, no longer recruiting to completed.
    • 30 Mar 2018 Status changed from active, no longer recruiting to completed.
    • 02 Feb 2016 Status changed from recruiting to active, no longer recruiting as per ClinicalTrials.gov record.

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