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A Phase I, Open Label, Randomized, Crossover Trial in Healthy Subjects to Investigate the Effect of Steady-state TMC278 on the Pharmacokinetics of a Single Dose of Digoxin.

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Trial Profile

A Phase I, Open Label, Randomized, Crossover Trial in Healthy Subjects to Investigate the Effect of Steady-state TMC278 on the Pharmacokinetics of a Single Dose of Digoxin.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 22 Jul 2017

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At a glance

  • Drugs Rilpivirine (Primary) ; Digoxin
  • Indications Atrial fibrillation; Atrial flutter; Heart failure; HIV-1 infections
  • Focus Pharmacokinetics
  • Sponsors Janssen R&D Ireland

    • Most Recent Events

    • 13 Jul 2013 New source identified and integrated (European Clinical Trials Database record: EudraCT2011-004159-38).
    • 29 Jun 2012 Company changed from Tibotec Pharmaceuticals Ireland to Janssen R&D Ireland as reported by ClinicalTrials.gov.
    • 29 Jun 2012 Actual end date Apr 2012 added as reported by ClinicalTrials.gov.

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