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Two Part Study to Investigate Pharmacokinetics (PK) and Pharamcodynamics (PD) of SB-705498 in Cough. Part A:Open Label Study in Healthy Subjects to Determine Exposure to SB-705498. Part B:Double-blind, Placebo Controlled, Cross Over Study to Investigate Effect of SB-705498 on Capsaicin Induced Cough and 24 Hour Cough Counts in Cough Patients.

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Trial Profile

Two Part Study to Investigate Pharmacokinetics (PK) and Pharamcodynamics (PD) of SB-705498 in Cough. Part A:Open Label Study in Healthy Subjects to Determine Exposure to SB-705498. Part B:Double-blind, Placebo Controlled, Cross Over Study to Investigate Effect of SB-705498 on Capsaicin Induced Cough and 24 Hour Cough Counts in Cough Patients.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Sep 2023

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At a glance

  • Drugs GSK 705498 (Primary)
  • Indications Allergic rhinitis; Cough; Rhinitis
  • Focus Pharmacodynamics; Pharmacokinetics; Therapeutic Use
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 01 Feb 2012 New trial record

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