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A 1-Year, Worldwide, Multicenter, Double-Blind, Randomized, Parallel, Placebo-Controlled Study to Assess the Efficacy and Tolerability of Anacetrapib When Added to Ongoing Statin Therapy With or Without Other Lipid Modifying Medication(s) in Patients With Heterozygous Familial Hypercholesterolemia

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A 1-Year, Worldwide, Multicenter, Double-Blind, Randomized, Parallel, Placebo-Controlled Study to Assess the Efficacy and Tolerability of Anacetrapib When Added to Ongoing Statin Therapy With or Without Other Lipid Modifying Medication(s) in Patients With Heterozygous Familial Hypercholesterolemia

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 May 2022

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At a glance

  • Drugs Anacetrapib (Primary)
  • Indications Hyperlipoproteinaemia type IIa
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms REALIZE
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 30 Aug 2017 Results of post-hoc, exploratory analysis evaluate the LDL-C-lowering efficacy of anacetrapib in patient subgroups defined by HeFH mutation type, were presented at the ESC Congress 2017: Annual Congress of the European Society of Cardiology.
    • 30 May 2015 Status changed from active, no longer recruiting to completed, as reported in The Lancet.
    • 30 May 2015 Results published in the Lancet.

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