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A Prospective, Randomised, Open-label Phase IIb Clinical Trial Assessing the Effect of Pegylated Interferon Alfa-2a (Pegasys)180 microg Once Weekly for 48 Weeks in Addition to an Ongoing Nucelos(t)Ide Based Treatment on Quantitative HBsAg Levels in Patients With Chronic HBeAg-negative Hepatitis B

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A Prospective, Randomised, Open-label Phase IIb Clinical Trial Assessing the Effect of Pegylated Interferon Alfa-2a (Pegasys)180 microg Once Weekly for 48 Weeks in Addition to an Ongoing Nucelos(t)Ide Based Treatment on Quantitative HBsAg Levels in Patients With Chronic HBeAg-negative Hepatitis B

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Peginterferon alfa-2a (Primary) ; Nucleosides; Nucleotides
  • Indications Hepatitis B
  • Focus Therapeutic Use
  • Acronyms PADD-ON

    • Most Recent Events

    • 14 Apr 2018 Primary endpoint (Difference in percentage of patients between treatment and comparator arm reaching a 1log10 decline of quantitative HBsAg after 48 weeks) has been met, according to the results presented at The International Liver Congress 2018
    • 14 Apr 2018 Results presented at The International Liver Congress 2018
    • 01 Mar 2018 Status changed from active, no longer recruiting to completed.

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