An Open-label, Phase II Study of Vemurafenib in Patients With BRAF V600 Mutation-positive Cancers
Latest Information Update: 07 Nov 2021
At a glance
- Drugs Vemurafenib (Primary) ; Cetuximab
- Indications Anaplastic astrocytoma; Cholangiocarcinoma; Colorectal cancer; Glioblastoma; Glioma; Multiple myeloma; Non-small cell lung cancer; Ovarian cancer; Solid tumours
- Focus Therapeutic Use
- Acronyms VE-BASKET
- Sponsors Roche
- 23 Oct 2018 Results (n=24) of Glioma cohort assessing the safety and efficacy of vemurafenib, published in the Journal of Clinical Oncology.
- 06 Nov 2017 According to a Genentech media release, the U.S. Food and Drug Administration (FDA) has approved Zelboraf (vemurafenib) for Erdheim-Chester disease (ECD) with BRAF V600 mutation. The approval is based on data from this study.
- 17 Oct 2017 Status changed from active, no longer recruiting to completed.