Cross-tumoral Phase 2 clinical trial exploring Crizotinib (PF-02341066) in patients with advanced tumours induced by causal alterations of either ALK or MET.

Trial Profile

Cross-tumoral Phase 2 clinical trial exploring Crizotinib (PF-02341066) in patients with advanced tumours induced by causal alterations of either ALK or MET.

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 05 May 2018

At a glance

  • Drugs Crizotinib (Primary)
  • Indications Alveolar soft part sarcoma; Anaplastic large cell lymphoma; Clear cell sarcoma; Muscle tissue neoplasms; Renal cancer; Rhabdomyosarcoma
  • Focus Therapeutic Use
  • Acronyms CREATE
  • Most Recent Events

    • 05 May 2018 Results assessing the safety and efficacy of crizotinib in patients with Clear-cell sarcoma (n=36), published in the Annals of Oncology
    • 19 Mar 2018 Primary endpoint (Objective response rate (CR+PR)) has not been met, according to results published in the European Journal of Cancer.
    • 19 Mar 2018 Results (n=19) published in the European Journal of Cancer.
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