De-ESCALaTE HPV: Determination of Epidermal growth factor receptor-inhibitor (cetuximab) versus Standard Chemotherapy (cisplatin) early And Late Toxicity Events in Human Papillomavirus-positive oropharyngeal squamous cell carcinoma.
Latest Information Update: 03 Oct 2023
At a glance
- Drugs Cetuximab (Primary) ; Cisplatin
- Indications Oropharyngeal cancer; Squamous cell cancer
- Focus Adverse reactions
- Acronyms De-ESCALaTE; De-ESCALaTE-HPV
- 01 Sep 2023 Results, as part of this study analyzing identify patients with low-risk HPVOPC at risk for recurrence by detection of HPV16 DNA in plasma and salivary rinses, published in the JAMA Otolaryngology-- Head and Neck Surgery
- 04 May 2022 Results from two trials TROG 12.01 and De-ESCALaTE assessing the quantification of ITIC CD103 could be used to identify a population of HPV-associated OPSCC with superior prognosis published in the Annals of Oncology
- 08 Jun 2021 Results assessing good and poor prognosis HPV associated oropharyngeal cancer based on CD103 immune cell expression in two studies ( TROG 12.01 and De-ESCALaTE ) presented at the 57th Annual Meeting of the American Society of Clinical Oncology.