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A Multi-Centre, Randomised, Double-Blind, Placebo-Controlled Safety and Efficacy Trial of a Dapivirine Vaginal Matrix Ring in Healthy HIV-Negative Women

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Trial Profile

A Multi-Centre, Randomised, Double-Blind, Placebo-Controlled Safety and Efficacy Trial of a Dapivirine Vaginal Matrix Ring in Healthy HIV-Negative Women

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 Nov 2022

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At a glance

  • Drugs Dapivirine (Primary)
  • Indications HIV-1 infections
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms The Ring Study

    • Most Recent Events

    • 08 Nov 2022 Results of an analysis from two clinical studies: DREAM and Ring-study assessing population-based genotyping performed on plasma samples collected longitudinally and next generation sequencing and phenotypic susceptibility testing done on plasma collected at seroconversion published in the Clinical Infectious Diseases
    • 03 Oct 2022 Results (n=150) of post hoc virology analysis assessing Clinical Presentation, Treatment Response and Virology Outcomes of Women who Seroconverted in the Dapivirine Vaginal Ring Trials published in the Clinical Infectious Diseases
    • 01 Feb 2022 Results (n=197) published in the Sexually Transmitted Infections

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