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A Phase I, Randomized, Open-label, Single-center Study to Assess the Pharmacokinetics of Vandetanib (CAPRELSA) in Healthy Subjects When a Single Oral Dose of Vandetanib 300 mg is Administered Alone and in Combination With Omeprazole or Ranitidine.

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Trial Profile

A Phase I, Randomized, Open-label, Single-center Study to Assess the Pharmacokinetics of Vandetanib (CAPRELSA) in Healthy Subjects When a Single Oral Dose of Vandetanib 300 mg is Administered Alone and in Combination With Omeprazole or Ranitidine.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Jan 2020

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At a glance

  • Drugs Omeprazole (Primary) ; Ranitidine (Primary) ; Vandetanib (Primary)
  • Indications Biliary cancer; Breast cancer; Duodenal ulcer; Dyspepsia; Gastric ulcer; Gastritis; Gastro-oesophageal reflux; Helicobacter infections; Peptic ulcer; Prostate cancer; Thyroid cancer; Zollinger-Ellison syndrome
  • Focus Pharmacokinetics
  • Sponsors Sanofi
  • Most Recent Events

    • 01 Sep 2012 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 03 Mar 2012 New trial record
    • 02 Mar 2012 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov.

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