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An Evaluation of Losmapimod in patients with Chronic Obstructive Pulmonary Disease (COPD) with systemic inflammation stratified using fibrinogen (EVOLUTION)

Trial Profile

An Evaluation of Losmapimod in patients with Chronic Obstructive Pulmonary Disease (COPD) with systemic inflammation stratified using fibrinogen (EVOLUTION)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Sep 2023

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At a glance

  • Drugs Losmapimod (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Therapeutic Use
  • Acronyms EVOLUTION

Most Recent Events

  • 18 May 2019 This trial has been completed in United Kingdom, according to European Clinical Trials Database.
  • 18 May 2016 Primary endpoint has not been met. (Endothelial function as measured by flow mediated dilatation), as per results presented at the 112th International Conference of the American Thoracic Society.
  • 18 May 2016 Primary endpoint has not been met. (Vascular inflammation on FDG PET-CT), as per results presented at the 112th International Conference of the American Thoracic Society.

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