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CYCLosporinE A in Reperfused Acute Myocardial Infarction Prospective, Controlled, Randomized, Multicentre Trial to Examine Whether a Single i.v. Bolus of Cyclosporine A Before PCI Can Reduce Myocardial Reperfusion Injury in Patients With STEMI.

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Trial Profile

CYCLosporinE A in Reperfused Acute Myocardial Infarction Prospective, Controlled, Randomized, Multicentre Trial to Examine Whether a Single i.v. Bolus of Cyclosporine A Before PCI Can Reduce Myocardial Reperfusion Injury in Patients With STEMI.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Ciclosporin (Primary)
  • Indications Myocardial infarction
  • Focus Therapeutic Use
  • Acronyms CYCLE
  • Most Recent Events

    • 02 Feb 2016 Primary endpoint of improvement of myocardial reperfusion, measured with ST-segment resolution greater than or equal to 70% has not been met, according to results published in the Journal of the American College of Cardiology.
    • 02 Feb 2016 Results published in the Journal of the American College of Cardiology
    • 15 Apr 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.

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