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Prophylaxis Versus Preemptive Therapy for the Prevention of CMV in High-Risk R-D+ Liver Transplant Recipients

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Trial Profile

Prophylaxis Versus Preemptive Therapy for the Prevention of CMV in High-Risk R-D+ Liver Transplant Recipients

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 26 Mar 2021

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At a glance

  • Drugs Valganciclovir (Primary)
  • Indications Cytomegalovirus infections
  • Focus Therapeutic Use
  • Acronyms CAPSIL

    • Most Recent Events

    • 23 Mar 2021 Results (n=79) assessing whether D+R- patients experience a marked increase in viral load despite prompt initiation of PET with valganciclovir at low threshold of viremia, published in the Journal of Infectious Diseases
    • 29 Jul 2020 Results of post-hoc analyses assessing recipient and donor risk factors associated with CMV viremia in D+R- liver transplant recipients who were managed with preemptive therapy as the strategy for CMV disease prevention published in the Journal of Infectious Diseases
    • 14 Apr 2020 Primary endpoint (Incidence of Cytomegalovirus (CMV) disease) has been met.

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