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A Multicenter, Randomized, Controlled Study To Evaluate The Efficacy and Safety of Short-Term Plasma Exchange Followed by Long-Term Plasmapheresis With Infusion of Human Albumin Combined With Intravenous Immunoglobulin In Patients With Mild-Moderate Alzheimer's Disease

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Trial Profile

A Multicenter, Randomized, Controlled Study To Evaluate The Efficacy and Safety of Short-Term Plasma Exchange Followed by Long-Term Plasmapheresis With Infusion of Human Albumin Combined With Intravenous Immunoglobulin In Patients With Mild-Moderate Alzheimer's Disease

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 24 Oct 2024

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At a glance

  • Drugs Albumin human (Primary) ; Immune globulin (Primary)
  • Indications Alzheimer's disease
  • Focus Registrational; Therapeutic Use
  • Acronyms AMBAR
  • Sponsors Grifols

    • Most Recent Events

    • 22 Oct 2024 According to Annovis Bio media release, data from the study will be presented as poster presentation at the 17th Clinical Trials on Alzheimers Disease (CTAD) conference. The event will be held from October 29 to November 1, 2024, in Madrid, Spain.
    • 20 Jul 2023 Results (n=296) assessing PE-Alb differential effects on metabolites between ApoE4 carriers and non-carriers presented at the Alzheimer's Association International Conference 2023
    • 01 Nov 2022 Results to detect structural and functional brain changes (n = 198) in Alzheimer's disease patients treated with therapeutic plasma exchange (PE) with albumin replacement, published in the European Journal of Nuclear Medicine and Molecular Imaging.

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