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Comparison of two antiretroviral regimens in HIV Post-exposure Prophylaxis: TDF-FTC (Truvada) + Lopinavir/ritonavir (kaletra) versus TDF-FTC (Truvada) + raltegravir (Isentress). A prospective, randomized, open clinical trial.

Trial Profile

Comparison of two antiretroviral regimens in HIV Post-exposure Prophylaxis: TDF-FTC (Truvada) + Lopinavir/ritonavir (kaletra) versus TDF-FTC (Truvada) + raltegravir (Isentress). A prospective, randomized, open clinical trial.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 22 Mar 2016

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At a glance

  • Drugs Raltegravir (Primary) ; Emtricitabine/tenofovir disoproxil fumarate; Lopinavir/ritonavir
  • Indications HIV infections
  • Focus Adverse reactions
  • Acronyms RAL-PEP
  • Most Recent Events

    • 18 Mar 2016 Results published in the Journal of Antimicrobial Chemotherapy
    • 25 May 2015 Status changed from recruiting to completed.
    • 11 Apr 2012 Additional lead trial centre, investigator (Garcia Felipe, MD) identified as reported by ClinicalTrials.gov.
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