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Phase III study of cisplatin plus S-1 (CS) compared with docetaxel and cisplatin plus S-1 (DCS) as first-line therapy for advanced gastric cancer (JCOG1013, GC_CS/DCS_P3 ADOPT)

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Trial Profile

Phase III study of cisplatin plus S-1 (CS) compared with docetaxel and cisplatin plus S-1 (DCS) as first-line therapy for advanced gastric cancer (JCOG1013, GC_CS/DCS_P3 ADOPT)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Feb 2024

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At a glance

  • Drugs Docetaxel (Primary) ; Cisplatin; Gimeracil/oteracil/tegafur
  • Indications Adenocarcinoma; Gastric cancer
  • Focus Therapeutic Use
  • Acronyms ADOPT
  • Most Recent Events

    • 20 Jan 2024 Results investigating the prognostic value of PD-L1 expression for survival in unresectable/recurrent GC patients receiving first-line chemotherapy without ICIs, presented at the 2024 Gastrointestinal Cancers Symposium
    • 03 Jan 2022 Results of this post-hoc analysis assessing the association of renal function with the safety and efficacy of the CS and DCS therapies for advanced gastric cancer patients published in the Japanese Journal of Clinical Oncology
    • 05 Jan 2021 Status changed from active, no longer recruiting to completed.

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