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A Phase III Randomized, Double-blind Study to Demonstrate the Antiviral Activity of Dolutegravir (DTG) 50 mg Twice Daily Versus Placebo Both Co-Administered With a Failing Antiretroviral Regimen Over Seven Days, Followed by an Open Label Phase With All Subjects Receiving DTG 50 mg Twice Daily Co-administered With an Optimised Background Regimen (OBR) in HIV-1 Infected, Integrase Inhibitor Therapy-Experienced and Resistant, Adults

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Trial Profile

A Phase III Randomized, Double-blind Study to Demonstrate the Antiviral Activity of Dolutegravir (DTG) 50 mg Twice Daily Versus Placebo Both Co-Administered With a Failing Antiretroviral Regimen Over Seven Days, Followed by an Open Label Phase With All Subjects Receiving DTG 50 mg Twice Daily Co-administered With an Optimised Background Regimen (OBR) in HIV-1 Infected, Integrase Inhibitor Therapy-Experienced and Resistant, Adults

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 25 Aug 2023

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At a glance

  • Drugs Dolutegravir (Primary) ; Antiretrovirals; Integrase inhibitors
  • Indications HIV-1 infections
  • Focus Therapeutic Use
  • Acronyms VIKING-4
  • Sponsors ViiV Healthcare

Most Recent Events

  • 30 Apr 2018 Status changed from active, no longer recruiting to completed.
  • 21 Nov 2012 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov record.
  • 14 Sep 2012 Planned End Date changed from 1 Nov 2012 to 1 Jun 2015 as reported by ClinicalTrials.gov record.

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