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A Phase Ib Trial of Gefitinib (EGFR Tyrosine Kinase Inhibitor, Iressa) in Combination With BKM120, an Oral Pan-class I PI3K Inhibitor in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFR

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A Phase Ib Trial of Gefitinib (EGFR Tyrosine Kinase Inhibitor, Iressa) in Combination With BKM120, an Oral Pan-class I PI3K Inhibitor in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFR

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 31 Mar 2023

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At a glance

  • Drugs Buparlisib (Primary) ; Gefitinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions

    • Most Recent Events

    • 28 Mar 2023 Status changed from active, no longer recruiting to completed.
    • 21 Aug 2018 Planned End Date changed from 1 Apr 2018 to 1 Apr 2019.
    • 01 Feb 2018 Planned End Date changed from 1 Dec 2017 to 1 Apr 2018.

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