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An Open-label, Phase I, Dose-escalation Study to Characterize the Safety, Tolerability, Pharmacokinetics, and Maximum Tolerated Dose of BAY 2010112, Given Once Daily by Subcutaneous Administration or by Continuous Intravenous Infusion, in Subjects With Castration-resistant Prostate Cancer

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Trial Profile

An Open-label, Phase I, Dose-escalation Study to Characterize the Safety, Tolerability, Pharmacokinetics, and Maximum Tolerated Dose of BAY 2010112, Given Once Daily by Subcutaneous Administration or by Continuous Intravenous Infusion, in Subjects With Castration-resistant Prostate Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Pasotuxizumab (Primary) ; Pasotuxizumab (Primary)
  • Indications Prostate cancer
  • Focus Adverse reactions; First in man
  • Sponsors Bayer
  • Most Recent Events

    • 15 Feb 2020 Results (n=16) assessing safety of pasotuxizumab in metastatic castration-resistant prostate cancer patients, presented at the 2020 Genitourinary Cancers Symposium.
    • 04 Jun 2019 Results presented at the 55th Annual Meeting of the American Society of Clinical Oncology
    • 02 Jun 2019 According to an Amgen media release, data from this trial were preseneted at the 55th Annual Meeting of the American Society of Clinical Oncology (ASCO) 2019.

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