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A Randomized, Double-blind, Placebo-controlled Phase III Study of Regorafenib Plus Best Supportive Care Versus Placebo Plus BSC in Asian Subjects With Metastatic Colorectal Cancer Who Have Progressed After Standard Therapy

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A Randomized, Double-blind, Placebo-controlled Phase III Study of Regorafenib Plus Best Supportive Care Versus Placebo Plus BSC in Asian Subjects With Metastatic Colorectal Cancer Who Have Progressed After Standard Therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 20 Aug 2022

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At a glance

  • Drugs Regorafenib (Primary)
  • Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms CONCUR
  • Sponsors Bayer

    • Most Recent Events

    • 02 Jul 2022 Results of a network analysis of data pooled from 3 global (ReDOS, CORRECT, RECOURSE) and 3 Asian (TERRA, Yoshino 2012, and CONCUR) studies assessed the impact of regorafenib dose optimization on clinical outcomes compared to best supportive care and TAS-102 in the treatment of relapsed/refractory metastatic colorectal cancer presented at the 24th World Congress on Gastrointestinal Cancer
    • 08 Jun 2021 Results evaluating findings of the five-dimensions of HRQoL in the two trials (CORRECT and CONCUR) presented at the 57th Annual Meeting of the American Society of Clinical Oncology
    • 01 May 2020 Results from NCT01103323; NCT01271712; NCT01584830; NCT01774344 evaluating Population pharmacokinetics of regorafenib in solid tumors in clinical practice considering enterohepatic circulation and food intake, published in the British Journal of Clinical Pharmacology

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