An International, Randomized, Open-label Phase I/II Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Adult Patients With Recurrent or Refractory Medulloblastomas Presenting an Activation of the Sonic Hedgehog (SHH) Pathway
Phase of Trial: Phase I/II
Latest Information Update: 06 Mar 2018
At a glance
- Drugs Temozolomide (Primary) ; Vismodegib (Primary)
- Indications Medulloblastoma
- Focus Adverse reactions; Therapeutic Use
- Acronyms MEVITEM
- 18 Oct 2016 Planned primary completion date changed from 1 Apr 2017 to 1 Apr 2018.
- 06 Sep 2016 Planned End Date changed from 1 Jun 2016 to 1 Oct 2018.
- 06 Sep 2016 Planned primary completion date changed from 1 Jun 2016 to 1 Apr 2017.