An International, Randomized, Open-label Phase I/II Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Adult Patients With Recurrent or Refractory Medulloblastomas Presenting an Activation of the Sonic Hedgehog (SHH) Pathway
Latest Information Update: 24 Nov 2021
At a glance
- Drugs Temozolomide (Primary) ; Vismodegib (Primary)
- Indications Medulloblastoma
- Focus Adverse reactions; Therapeutic Use
- Acronyms MEVITEM
- 02 Nov 2021 Results published in the Neuro-Oncology
- 20 Sep 2018 Status changed from recruiting to discontinued as the number of successes is not reached at the end of first stage of the phase II
- 18 Oct 2016 Planned primary completion date changed from 1 Apr 2017 to 1 Apr 2018.