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An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain PDE4 Engagement, Pharmacokinetics and Safety of Single Oral Doses of GSK356278, Using 11C-(R)-Rolipram as a PET Ligand(s)

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Trial Profile

An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain PDE4 Engagement, Pharmacokinetics and Safety of Single Oral Doses of GSK356278, Using 11C-(R)-Rolipram as a PET Ligand(s)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Dec 2023

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At a glance

  • Drugs GSK 356278 (Primary)
  • Indications Huntington's disease
  • Focus Pharmacodynamics; Pharmacokinetics
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 24 May 2012 New trial record

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