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A Multicenter, Randomized, Double-masked, Placebo-controlled Phase II Study to Assess the Safety and Efficacy of a Standardized Orally Administered Silymarin Preparation (Legalon) for the Treatment of Patients With Chronic Hepatitis C Who Failed Conventional Antiviral Therapy.

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A Multicenter, Randomized, Double-masked, Placebo-controlled Phase II Study to Assess the Safety and Efficacy of a Standardized Orally Administered Silymarin Preparation (Legalon) for the Treatment of Patients With Chronic Hepatitis C Who Failed Conventional Antiviral Therapy.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Jul 2014

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At a glance

  • Drugs Silibinin (Primary)
  • Indications Hepatitis C
  • Focus Adverse reactions; Biomarker; Pharmacodynamics; Therapeutic Use
  • Acronyms SyNCH

    • Most Recent Events

    • 18 Jul 2012 Results published in JAMA: the Journal of the American Medical Association.
    • 27 May 2012 New trial record
    • 22 May 2012 Substudy results presented at Digestive Disease Week 2012.

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