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A Single Blind, Randomized, Placebo-controlled, Dose Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Parameters of Repeat Doses of GSK2330672 in Healthy Volunteers, Given Alone and With a Single Day of Dosing With GSK1614235

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A Single Blind, Randomized, Placebo-controlled, Dose Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Parameters of Repeat Doses of GSK2330672 in Healthy Volunteers, Given Alone and With a Single Day of Dosing With GSK1614235

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 Aug 2022

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At a glance

  • Drugs GSK 1614235 (Primary) ; Linerixibat (Primary)
  • Indications Cholestasis; Primary biliary cirrhosis; Pruritus; Type 2 diabetes mellitus
  • Focus Adverse reactions
  • Sponsors GSK

    • Most Recent Events

    • 26 Jun 2022 Results from three Phase 1 studies 114985,116511, 205808 and from patients with PBC in two Phase 2 stud, 201000 and other study, presented at The International Liver Congress 2022
    • 01 Mar 2013 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 09 Nov 2012 Planned End Date changed from 1 Oct 2012 to 1 Nov 2012 as reported by ClinicalTrials.gov.

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